Tricocet
Brand names,
Tricocet
Analogs
Tricocet
Brand Names Mixture
Tricocet
Chemical_Formula
C6H9N3O3
Tricocet
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Tricocet
fda sheet
Tricocet
msds (material safety sheet)
Tricocet
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Tricocet
Molecular Weight
171.154 g/mol
Tricocet
Melting Point
160 oC
Tricocet
H2O Solubility
<0.1g/100mL
Tricocet
State
Solid
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LogP
-0.262
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Dosage Forms
Tablet; Intravenous injection
Tricocet
Indication
Treatment of acute acne rosacea
Tricocet
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Tricocet
Absorption
Well absorbed
Tricocet
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Tricocet
Patient Information
Tricocet
Organisms Affected
Bacteria and protozoa