Giatricol
Brand names,
Giatricol
Analogs
Giatricol
Brand Names Mixture
Giatricol
Chemical_Formula
C6H9N3O3
Giatricol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Giatricol
fda sheet
Giatricol
msds (material safety sheet)
Giatricol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Giatricol
Molecular Weight
171.154 g/mol
Giatricol
Melting Point
160 oC
Giatricol
H2O Solubility
<0.1g/100mL
Giatricol
State
Solid
Giatricol
LogP
-0.262
Giatricol
Dosage Forms
Tablet; Intravenous injection
Giatricol
Indication
Treatment of acute acne rosacea
Giatricol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Giatricol
Absorption
Well absorbed
Giatricol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Giatricol
Patient Information
Giatricol
Organisms Affected
Bacteria and protozoa