Trichopol
Brand names,
Trichopol
Analogs
Trichopol
Brand Names Mixture
Trichopol
Chemical_Formula
C6H9N3O3
Trichopol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trichopol
fda sheet
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msds (material safety sheet)
Trichopol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trichopol
Molecular Weight
171.154 g/mol
Trichopol
Melting Point
160 oC
Trichopol
H2O Solubility
<0.1g/100mL
Trichopol
State
Solid
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LogP
-0.262
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Dosage Forms
Tablet; Intravenous injection
Trichopol
Indication
Treatment of acute acne rosacea
Trichopol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trichopol
Absorption
Well absorbed
Trichopol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trichopol
Patient Information
Trichopol
Organisms Affected
Bacteria and protozoa