Flagemona
Brand names,
Flagemona
Analogs
Flagemona
Brand Names Mixture
Flagemona
Chemical_Formula
C6H9N3O3
Flagemona
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flagemona
fda sheet
Flagemona
msds (material safety sheet)
Flagemona
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flagemona
Molecular Weight
171.154 g/mol
Flagemona
Melting Point
160 oC
Flagemona
H2O Solubility
<0.1g/100mL
Flagemona
State
Solid
Flagemona
LogP
-0.262
Flagemona
Dosage Forms
Tablet; Intravenous injection
Flagemona
Indication
Treatment of acute acne rosacea
Flagemona
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flagemona
Absorption
Well absorbed
Flagemona
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flagemona
Patient Information
Flagemona
Organisms Affected
Bacteria and protozoa