Metro I.V.
Brand names,
Metro I.V.
Analogs
Metro I.V.
Brand Names Mixture
Metro I.V.
Chemical_Formula
C6H9N3O3
Metro I.V.
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metro I.V.
fda sheet
Metro I.V.
msds (material safety sheet)
Metro I.V.
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metro I.V.
Molecular Weight
171.154 g/mol
Metro I.V.
Melting Point
160 oC
Metro I.V.
H2O Solubility
<0.1g/100mL
Metro I.V.
State
Solid
Metro I.V.
LogP
-0.262
Metro I.V.
Dosage Forms
Tablet; Intravenous injection
Metro I.V.
Indication
Treatment of acute acne rosacea
Metro I.V.
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metro I.V.
Absorption
Well absorbed
Metro I.V.
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metro I.V.
Patient Information
Metro I.V.
Organisms Affected
Bacteria and protozoa