Metronidaz
Brand names,
Metronidaz
Analogs
Metronidaz
Brand Names Mixture
Metronidaz
Chemical_Formula
C6H9N3O3
Metronidaz
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidaz
fda sheet
Metronidaz
msds (material safety sheet)
Metronidaz
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidaz
Molecular Weight
171.154 g/mol
Metronidaz
Melting Point
160 oC
Metronidaz
H2O Solubility
<0.1g/100mL
Metronidaz
State
Solid
Metronidaz
LogP
-0.262
Metronidaz
Dosage Forms
Tablet; Intravenous injection
Metronidaz
Indication
Treatment of acute acne rosacea
Metronidaz
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidaz
Absorption
Well absorbed
Metronidaz
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidaz
Patient Information
Metronidaz
Organisms Affected
Bacteria and protozoa