Trikozol
Brand names,
Trikozol
Analogs
Trikozol
Brand Names Mixture
Trikozol
Chemical_Formula
C6H9N3O3
Trikozol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trikozol
fda sheet
Trikozol
msds (material safety sheet)
Trikozol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trikozol
Molecular Weight
171.154 g/mol
Trikozol
Melting Point
160 oC
Trikozol
H2O Solubility
<0.1g/100mL
Trikozol
State
Solid
Trikozol
LogP
-0.262
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Dosage Forms
Tablet; Intravenous injection
Trikozol
Indication
Treatment of acute acne rosacea
Trikozol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trikozol
Absorption
Well absorbed
Trikozol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trikozol
Patient Information
Trikozol
Organisms Affected
Bacteria and protozoa