Trichomol
Brand names,
Trichomol
Analogs
Trichomol
Brand Names Mixture
Trichomol
Chemical_Formula
C6H9N3O3
Trichomol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trichomol
fda sheet
Trichomol
msds (material safety sheet)
Trichomol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trichomol
Molecular Weight
171.154 g/mol
Trichomol
Melting Point
160 oC
Trichomol
H2O Solubility
<0.1g/100mL
Trichomol
State
Solid
Trichomol
LogP
-0.262
Trichomol
Dosage Forms
Tablet; Intravenous injection
Trichomol
Indication
Treatment of acute acne rosacea
Trichomol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trichomol
Absorption
Well absorbed
Trichomol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trichomol
Patient Information
Trichomol
Organisms Affected
Bacteria and protozoa