Trivazol
Brand names,
Trivazol
Analogs
Trivazol
Brand Names Mixture
Trivazol
Chemical_Formula
C6H9N3O3
Trivazol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trivazol
fda sheet
Trivazol
msds (material safety sheet)
Trivazol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trivazol
Molecular Weight
171.154 g/mol
Trivazol
Melting Point
160 oC
Trivazol
H2O Solubility
<0.1g/100mL
Trivazol
State
Solid
Trivazol
LogP
-0.262
Trivazol
Dosage Forms
Tablet; Intravenous injection
Trivazol
Indication
Treatment of acute acne rosacea
Trivazol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trivazol
Absorption
Well absorbed
Trivazol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trivazol
Patient Information
Trivazol
Organisms Affected
Bacteria and protozoa