Metrogel-Vaginal
Brand names,
Metrogel-Vaginal
Analogs
Metrogel-Vaginal
Brand Names Mixture
Metrogel-Vaginal
Chemical_Formula
C6H9N3O3
Metrogel-Vaginal
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrogel-Vaginal
fda sheet
Metrogel-Vaginal
msds (material safety sheet)
Metrogel-Vaginal
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrogel-Vaginal
Molecular Weight
171.154 g/mol
Metrogel-Vaginal
Melting Point
160 oC
Metrogel-Vaginal
H2O Solubility
<0.1g/100mL
Metrogel-Vaginal
State
Solid
Metrogel-Vaginal
LogP
-0.262
Metrogel-Vaginal
Dosage Forms
Tablet; Intravenous injection
Metrogel-Vaginal
Indication
Treatment of acute acne rosacea
Metrogel-Vaginal
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrogel-Vaginal
Absorption
Well absorbed
Metrogel-Vaginal
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrogel-Vaginal
Patient Information
Metrogel-Vaginal
Organisms Affected
Bacteria and protozoa