Protostat
Brand names,
Protostat
Analogs
Protostat
Brand Names Mixture
Protostat
Chemical_Formula
C6H9N3O3
Protostat
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Protostat
fda sheet
Protostat
msds (material safety sheet)
Protostat
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Protostat
Molecular Weight
171.154 g/mol
Protostat
Melting Point
160 oC
Protostat
H2O Solubility
<0.1g/100mL
Protostat
State
Solid
Protostat
LogP
-0.262
Protostat
Dosage Forms
Tablet; Intravenous injection
Protostat
Indication
Treatment of acute acne rosacea
Protostat
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Protostat
Absorption
Well absorbed
Protostat
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Protostat
Patient Information
Protostat
Organisms Affected
Bacteria and protozoa