Metromidol
Brand names,
Metromidol
Analogs
Metromidol
Brand Names Mixture
Metromidol
Chemical_Formula
C6H9N3O3
Metromidol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metromidol
fda sheet
Metromidol
msds (material safety sheet)
Metromidol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metromidol
Molecular Weight
171.154 g/mol
Metromidol
Melting Point
160 oC
Metromidol
H2O Solubility
<0.1g/100mL
Metromidol
State
Solid
Metromidol
LogP
-0.262
Metromidol
Dosage Forms
Tablet; Intravenous injection
Metromidol
Indication
Treatment of acute acne rosacea
Metromidol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metromidol
Absorption
Well absorbed
Metromidol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metromidol
Patient Information
Metromidol
Organisms Affected
Bacteria and protozoa