Metrocream
Brand names,
Metrocream
Analogs
Metrocream
Brand Names Mixture
Metrocream
Chemical_Formula
C6H9N3O3
Metrocream
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrocream
fda sheet
Metrocream
msds (material safety sheet)
Metrocream
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrocream
Molecular Weight
171.154 g/mol
Metrocream
Melting Point
160 oC
Metrocream
H2O Solubility
<0.1g/100mL
Metrocream
State
Solid
Metrocream
LogP
-0.262
Metrocream
Dosage Forms
Tablet; Intravenous injection
Metrocream
Indication
Treatment of acute acne rosacea
Metrocream
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrocream
Absorption
Well absorbed
Metrocream
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrocream
Patient Information
Metrocream
Organisms Affected
Bacteria and protozoa