Metronidazolo
Brand names,
Metronidazolo
Analogs
Metronidazolo
Brand Names Mixture
Metronidazolo
Chemical_Formula
C6H9N3O3
Metronidazolo
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidazolo
fda sheet
Metronidazolo
msds (material safety sheet)
Metronidazolo
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidazolo
Molecular Weight
171.154 g/mol
Metronidazolo
Melting Point
160 oC
Metronidazolo
H2O Solubility
<0.1g/100mL
Metronidazolo
State
Solid
Metronidazolo
LogP
-0.262
Metronidazolo
Dosage Forms
Tablet; Intravenous injection
Metronidazolo
Indication
Treatment of acute acne rosacea
Metronidazolo
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidazolo
Absorption
Well absorbed
Metronidazolo
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidazolo
Patient Information
Metronidazolo
Organisms Affected
Bacteria and protozoa