Metrolag
Brand names,
Metrolag
Analogs
Metrolag
Brand Names Mixture
Metrolag
Chemical_Formula
C6H9N3O3
Metrolag
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrolag
fda sheet
Metrolag
msds (material safety sheet)
Metrolag
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrolag
Molecular Weight
171.154 g/mol
Metrolag
Melting Point
160 oC
Metrolag
H2O Solubility
<0.1g/100mL
Metrolag
State
Solid
Metrolag
LogP
-0.262
Metrolag
Dosage Forms
Tablet; Intravenous injection
Metrolag
Indication
Treatment of acute acne rosacea
Metrolag
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrolag
Absorption
Well absorbed
Metrolag
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrolag
Patient Information
Metrolag
Organisms Affected
Bacteria and protozoa