Satric
Brand names,
Satric
Analogs
Satric
Brand Names Mixture
Satric
Chemical_Formula
C6H9N3O3
Satric
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
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fda sheet
Satric
msds (material safety sheet)
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Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Satric
Molecular Weight
171.154 g/mol
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Melting Point
160 oC
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H2O Solubility
<0.1g/100mL
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State
Solid
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LogP
-0.262
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Dosage Forms
Tablet; Intravenous injection
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Indication
Treatment of acute acne rosacea
Satric
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Satric
Absorption
Well absorbed
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side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Satric
Patient Information
Satric
Organisms Affected
Bacteria and protozoa