Flagesol
Brand names,
Flagesol
Analogs
Flagesol
Brand Names Mixture
Flagesol
Chemical_Formula
C6H9N3O3
Flagesol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flagesol
fda sheet
Flagesol
msds (material safety sheet)
Flagesol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flagesol
Molecular Weight
171.154 g/mol
Flagesol
Melting Point
160 oC
Flagesol
H2O Solubility
<0.1g/100mL
Flagesol
State
Solid
Flagesol
LogP
-0.262
Flagesol
Dosage Forms
Tablet; Intravenous injection
Flagesol
Indication
Treatment of acute acne rosacea
Flagesol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flagesol
Absorption
Well absorbed
Flagesol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flagesol
Patient Information
Flagesol
Organisms Affected
Bacteria and protozoa