Deflamon
Brand names,
Deflamon
Analogs
Deflamon
Brand Names Mixture
Deflamon
Chemical_Formula
C6H9N3O3
Deflamon
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Deflamon
fda sheet
Deflamon
msds (material safety sheet)
Deflamon
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Deflamon
Molecular Weight
171.154 g/mol
Deflamon
Melting Point
160 oC
Deflamon
H2O Solubility
<0.1g/100mL
Deflamon
State
Solid
Deflamon
LogP
-0.262
Deflamon
Dosage Forms
Tablet; Intravenous injection
Deflamon
Indication
Treatment of acute acne rosacea
Deflamon
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Deflamon
Absorption
Well absorbed
Deflamon
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Deflamon
Patient Information
Deflamon
Organisms Affected
Bacteria and protozoa