Metro I.V. In Plastic Container
Brand names,
Metro I.V. In Plastic Container
Analogs
Metro I.V. In Plastic Container
Brand Names Mixture
Metro I.V. In Plastic Container
Chemical_Formula
C6H9N3O3
Metro I.V. In Plastic Container
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metro I.V. In Plastic Container
fda sheet
Metro I.V. In Plastic Container
msds (material safety sheet)
Metro I.V. In Plastic Container
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metro I.V. In Plastic Container
Molecular Weight
171.154 g/mol
Metro I.V. In Plastic Container
Melting Point
160 oC
Metro I.V. In Plastic Container
H2O Solubility
<0.1g/100mL
Metro I.V. In Plastic Container
State
Solid
Metro I.V. In Plastic Container
LogP
-0.262
Metro I.V. In Plastic Container
Dosage Forms
Tablet; Intravenous injection
Metro I.V. In Plastic Container
Indication
Treatment of acute acne rosacea
Metro I.V. In Plastic Container
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metro I.V. In Plastic Container
Absorption
Well absorbed
Metro I.V. In Plastic Container
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metro I.V. In Plastic Container
Patient Information
Metro I.V. In Plastic Container
Organisms Affected
Bacteria and protozoa