Efloran
Brand names,
Efloran
Analogs
Efloran
Brand Names Mixture
Efloran
Chemical_Formula
C6H9N3O3
Efloran
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Efloran
fda sheet
Efloran
msds (material safety sheet)
Efloran
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Efloran
Molecular Weight
171.154 g/mol
Efloran
Melting Point
160 oC
Efloran
H2O Solubility
<0.1g/100mL
Efloran
State
Solid
Efloran
LogP
-0.262
Efloran
Dosage Forms
Tablet; Intravenous injection
Efloran
Indication
Treatment of acute acne rosacea
Efloran
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Efloran
Absorption
Well absorbed
Efloran
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Efloran
Patient Information
Efloran
Organisms Affected
Bacteria and protozoa