Trikacide
Brand names,
Trikacide
Analogs
Trikacide
Brand Names Mixture
Trikacide
Chemical_Formula
C6H9N3O3
Trikacide
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trikacide
fda sheet
Trikacide
msds (material safety sheet)
Trikacide
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trikacide
Molecular Weight
171.154 g/mol
Trikacide
Melting Point
160 oC
Trikacide
H2O Solubility
<0.1g/100mL
Trikacide
State
Solid
Trikacide
LogP
-0.262
Trikacide
Dosage Forms
Tablet; Intravenous injection
Trikacide
Indication
Treatment of acute acne rosacea
Trikacide
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trikacide
Absorption
Well absorbed
Trikacide
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trikacide
Patient Information
Trikacide
Organisms Affected
Bacteria and protozoa