Metronidazol
Brand names,
Metronidazol
Analogs
Metronidazol
Brand Names Mixture
Metronidazol
Chemical_Formula
C6H9N3O3
Metronidazol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidazol
fda sheet
Metronidazol
msds (material safety sheet)
Metronidazol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidazol
Molecular Weight
171.154 g/mol
Metronidazol
Melting Point
160 oC
Metronidazol
H2O Solubility
<0.1g/100mL
Metronidazol
State
Solid
Metronidazol
LogP
-0.262
Metronidazol
Dosage Forms
Tablet; Intravenous injection
Metronidazol
Indication
Treatment of acute acne rosacea
Metronidazol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidazol
Absorption
Well absorbed
Metronidazol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidazol
Patient Information
Metronidazol
Organisms Affected
Bacteria and protozoa