Danizol
Brand names,
Danizol
Analogs
Danizol
Brand Names Mixture
Danizol
Chemical_Formula
C6H9N3O3
Danizol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Danizol
fda sheet
Danizol
msds (material safety sheet)
Danizol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Danizol
Molecular Weight
171.154 g/mol
Danizol
Melting Point
160 oC
Danizol
H2O Solubility
<0.1g/100mL
Danizol
State
Solid
Danizol
LogP
-0.262
Danizol
Dosage Forms
Tablet; Intravenous injection
Danizol
Indication
Treatment of acute acne rosacea
Danizol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Danizol
Absorption
Well absorbed
Danizol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Danizol
Patient Information
Danizol
Organisms Affected
Bacteria and protozoa