Arilin
Brand names,
Arilin
Analogs
Arilin
Brand Names Mixture
Arilin
Chemical_Formula
C6H9N3O3
Arilin
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Arilin
fda sheet
Arilin
msds (material safety sheet)
Arilin
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Arilin
Molecular Weight
171.154 g/mol
Arilin
Melting Point
160 oC
Arilin
H2O Solubility
<0.1g/100mL
Arilin
State
Solid
Arilin
LogP
-0.262
Arilin
Dosage Forms
Tablet; Intravenous injection
Arilin
Indication
Treatment of acute acne rosacea
Arilin
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Arilin
Absorption
Well absorbed
Arilin
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Arilin
Patient Information
Arilin
Organisms Affected
Bacteria and protozoa