Vagimid
Brand names,
Vagimid
Analogs
Vagimid
Brand Names Mixture
Vagimid
Chemical_Formula
C6H9N3O3
Vagimid
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Vagimid
fda sheet
Vagimid
msds (material safety sheet)
Vagimid
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Vagimid
Molecular Weight
171.154 g/mol
Vagimid
Melting Point
160 oC
Vagimid
H2O Solubility
<0.1g/100mL
Vagimid
State
Solid
Vagimid
LogP
-0.262
Vagimid
Dosage Forms
Tablet; Intravenous injection
Vagimid
Indication
Treatment of acute acne rosacea
Vagimid
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Vagimid
Absorption
Well absorbed
Vagimid
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Vagimid
Patient Information
Vagimid
Organisms Affected
Bacteria and protozoa