Nidagel
Brand names,
Nidagel
Analogs
Nidagel
Brand Names Mixture
Nidagel
Chemical_Formula
C6H9N3O3
Nidagel
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Nidagel
fda sheet
Nidagel
msds (material safety sheet)
Nidagel
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Nidagel
Molecular Weight
171.154 g/mol
Nidagel
Melting Point
160 oC
Nidagel
H2O Solubility
<0.1g/100mL
Nidagel
State
Solid
Nidagel
LogP
-0.262
Nidagel
Dosage Forms
Tablet; Intravenous injection
Nidagel
Indication
Treatment of acute acne rosacea
Nidagel
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Nidagel
Absorption
Well absorbed
Nidagel
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Nidagel
Patient Information
Nidagel
Organisms Affected
Bacteria and protozoa