Metrogel
Brand names,
Metrogel
Analogs
Metrogel
Brand Names Mixture
Metrogel
Chemical_Formula
C6H9N3O3
Metrogel
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrogel
fda sheet
Metrogel
msds (material safety sheet)
Metrogel
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrogel
Molecular Weight
171.154 g/mol
Metrogel
Melting Point
160 oC
Metrogel
H2O Solubility
<0.1g/100mL
Metrogel
State
Solid
Metrogel
LogP
-0.262
Metrogel
Dosage Forms
Tablet; Intravenous injection
Metrogel
Indication
Treatment of acute acne rosacea
Metrogel
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrogel
Absorption
Well absorbed
Metrogel
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrogel
Patient Information
Metrogel
Organisms Affected
Bacteria and protozoa