Metrolyl
Brand names,
Metrolyl
Analogs
Metrolyl
Brand Names Mixture
Metrolyl
Chemical_Formula
C6H9N3O3
Metrolyl
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrolyl
fda sheet
Metrolyl
msds (material safety sheet)
Metrolyl
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrolyl
Molecular Weight
171.154 g/mol
Metrolyl
Melting Point
160 oC
Metrolyl
H2O Solubility
<0.1g/100mL
Metrolyl
State
Solid
Metrolyl
LogP
-0.262
Metrolyl
Dosage Forms
Tablet; Intravenous injection
Metrolyl
Indication
Treatment of acute acne rosacea
Metrolyl
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrolyl
Absorption
Well absorbed
Metrolyl
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrolyl
Patient Information
Metrolyl
Organisms Affected
Bacteria and protozoa