Benzoylmetronildazole
Brand names,
Benzoylmetronildazole
Analogs
Benzoylmetronildazole
Brand Names Mixture
Benzoylmetronildazole
Chemical_Formula
C6H9N3O3
Benzoylmetronildazole
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Benzoylmetronildazole
fda sheet
Benzoylmetronildazole
msds (material safety sheet)
Benzoylmetronildazole
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Benzoylmetronildazole
Molecular Weight
171.154 g/mol
Benzoylmetronildazole
Melting Point
160 oC
Benzoylmetronildazole
H2O Solubility
<0.1g/100mL
Benzoylmetronildazole
State
Solid
Benzoylmetronildazole
LogP
-0.262
Benzoylmetronildazole
Dosage Forms
Tablet; Intravenous injection
Benzoylmetronildazole
Indication
Treatment of acute acne rosacea
Benzoylmetronildazole
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Benzoylmetronildazole
Absorption
Well absorbed
Benzoylmetronildazole
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Benzoylmetronildazole
Patient Information
Benzoylmetronildazole
Organisms Affected
Bacteria and protozoa