Trichex
Brand names,
Trichex
Analogs
Trichex
Brand Names Mixture
Trichex
Chemical_Formula
C6H9N3O3
Trichex
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trichex
fda sheet
Trichex
msds (material safety sheet)
Trichex
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trichex
Molecular Weight
171.154 g/mol
Trichex
Melting Point
160 oC
Trichex
H2O Solubility
<0.1g/100mL
Trichex
State
Solid
Trichex
LogP
-0.262
Trichex
Dosage Forms
Tablet; Intravenous injection
Trichex
Indication
Treatment of acute acne rosacea
Trichex
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trichex
Absorption
Well absorbed
Trichex
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trichex
Patient Information
Trichex
Organisms Affected
Bacteria and protozoa