Tricho-Gynaedron
Brand names,
Tricho-Gynaedron
Analogs
Tricho-Gynaedron
Brand Names Mixture
Tricho-Gynaedron
Chemical_Formula
C6H9N3O3
Tricho-Gynaedron
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Tricho-Gynaedron
fda sheet
Tricho-Gynaedron
msds (material safety sheet)
Tricho-Gynaedron
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Tricho-Gynaedron
Molecular Weight
171.154 g/mol
Tricho-Gynaedron
Melting Point
160 oC
Tricho-Gynaedron
H2O Solubility
<0.1g/100mL
Tricho-Gynaedron
State
Solid
Tricho-Gynaedron
LogP
-0.262
Tricho-Gynaedron
Dosage Forms
Tablet; Intravenous injection
Tricho-Gynaedron
Indication
Treatment of acute acne rosacea
Tricho-Gynaedron
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Tricho-Gynaedron
Absorption
Well absorbed
Tricho-Gynaedron
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Tricho-Gynaedron
Patient Information
Tricho-Gynaedron
Organisms Affected
Bacteria and protozoa