Flagyl I.V.
Brand names,
Flagyl I.V.
Analogs
Flagyl I.V.
Brand Names Mixture
Flagyl I.V.
Chemical_Formula
C6H9N3O3
Flagyl I.V.
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flagyl I.V.
fda sheet
Flagyl I.V.
msds (material safety sheet)
Flagyl I.V.
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flagyl I.V.
Molecular Weight
171.154 g/mol
Flagyl I.V.
Melting Point
160 oC
Flagyl I.V.
H2O Solubility
<0.1g/100mL
Flagyl I.V.
State
Solid
Flagyl I.V.
LogP
-0.262
Flagyl I.V.
Dosage Forms
Tablet; Intravenous injection
Flagyl I.V.
Indication
Treatment of acute acne rosacea
Flagyl I.V.
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flagyl I.V.
Absorption
Well absorbed
Flagyl I.V.
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flagyl I.V.
Patient Information
Flagyl I.V.
Organisms Affected
Bacteria and protozoa