Gineflavir
Brand names,
Gineflavir
Analogs
Gineflavir
Brand Names Mixture
Gineflavir
Chemical_Formula
C6H9N3O3
Gineflavir
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Gineflavir
fda sheet
Gineflavir
msds (material safety sheet)
Gineflavir
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Gineflavir
Molecular Weight
171.154 g/mol
Gineflavir
Melting Point
160 oC
Gineflavir
H2O Solubility
<0.1g/100mL
Gineflavir
State
Solid
Gineflavir
LogP
-0.262
Gineflavir
Dosage Forms
Tablet; Intravenous injection
Gineflavir
Indication
Treatment of acute acne rosacea
Gineflavir
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Gineflavir
Absorption
Well absorbed
Gineflavir
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Gineflavir
Patient Information
Gineflavir
Organisms Affected
Bacteria and protozoa