Metrolotion
Brand names,
Metrolotion
Analogs
Metrolotion
Brand Names Mixture
Metrolotion
Chemical_Formula
C6H9N3O3
Metrolotion
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metrolotion
fda sheet
Metrolotion
msds (material safety sheet)
Metrolotion
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metrolotion
Molecular Weight
171.154 g/mol
Metrolotion
Melting Point
160 oC
Metrolotion
H2O Solubility
<0.1g/100mL
Metrolotion
State
Solid
Metrolotion
LogP
-0.262
Metrolotion
Dosage Forms
Tablet; Intravenous injection
Metrolotion
Indication
Treatment of acute acne rosacea
Metrolotion
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metrolotion
Absorption
Well absorbed
Metrolotion
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metrolotion
Patient Information
Metrolotion
Organisms Affected
Bacteria and protozoa