Flagil
Brand names,
Flagil
Analogs
Flagil
Brand Names Mixture
Flagil
Chemical_Formula
C6H9N3O3
Flagil
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flagil
fda sheet
Flagil
msds (material safety sheet)
Flagil
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flagil
Molecular Weight
171.154 g/mol
Flagil
Melting Point
160 oC
Flagil
H2O Solubility
<0.1g/100mL
Flagil
State
Solid
Flagil
LogP
-0.262
Flagil
Dosage Forms
Tablet; Intravenous injection
Flagil
Indication
Treatment of acute acne rosacea
Flagil
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flagil
Absorption
Well absorbed
Flagil
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flagil
Patient Information
Flagil
Organisms Affected
Bacteria and protozoa