Neo-Tric
Brand names,
Neo-Tric
Analogs
Neo-Tric
Brand Names Mixture
Neo-Tric
Chemical_Formula
C6H9N3O3
Neo-Tric
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Neo-Tric
fda sheet
Neo-Tric
msds (material safety sheet)
Neo-Tric
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Neo-Tric
Molecular Weight
171.154 g/mol
Neo-Tric
Melting Point
160 oC
Neo-Tric
H2O Solubility
<0.1g/100mL
Neo-Tric
State
Solid
Neo-Tric
LogP
-0.262
Neo-Tric
Dosage Forms
Tablet; Intravenous injection
Neo-Tric
Indication
Treatment of acute acne rosacea
Neo-Tric
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Neo-Tric
Absorption
Well absorbed
Neo-Tric
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Neo-Tric
Patient Information
Neo-Tric
Organisms Affected
Bacteria and protozoa