Bayer 5360
Brand names,
Bayer 5360
Analogs
Bayer 5360
Brand Names Mixture
Bayer 5360
Chemical_Formula
C6H9N3O3
Bayer 5360
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Bayer 5360
fda sheet
Bayer 5360
msds (material safety sheet)
Bayer 5360
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Bayer 5360
Molecular Weight
171.154 g/mol
Bayer 5360
Melting Point
160 oC
Bayer 5360
H2O Solubility
<0.1g/100mL
Bayer 5360
State
Solid
Bayer 5360
LogP
-0.262
Bayer 5360
Dosage Forms
Tablet; Intravenous injection
Bayer 5360
Indication
Treatment of acute acne rosacea
Bayer 5360
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Bayer 5360
Absorption
Well absorbed
Bayer 5360
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Bayer 5360
Patient Information
Bayer 5360
Organisms Affected
Bacteria and protozoa