Mexibol
Brand names,
Mexibol
Analogs
Mexibol
Brand Names Mixture
Mexibol
Chemical_Formula
C6H9N3O3
Mexibol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Mexibol
fda sheet
Mexibol
msds (material safety sheet)
Mexibol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Mexibol
Molecular Weight
171.154 g/mol
Mexibol
Melting Point
160 oC
Mexibol
H2O Solubility
<0.1g/100mL
Mexibol
State
Solid
Mexibol
LogP
-0.262
Mexibol
Dosage Forms
Tablet; Intravenous injection
Mexibol
Indication
Treatment of acute acne rosacea
Mexibol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Mexibol
Absorption
Well absorbed
Mexibol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Mexibol
Patient Information
Mexibol
Organisms Affected
Bacteria and protozoa