Elyzol
Brand names,
Elyzol
Analogs
Elyzol
Brand Names Mixture
Elyzol
Chemical_Formula
C6H9N3O3
Elyzol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Elyzol
fda sheet
Elyzol
msds (material safety sheet)
Elyzol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Elyzol
Molecular Weight
171.154 g/mol
Elyzol
Melting Point
160 oC
Elyzol
H2O Solubility
<0.1g/100mL
Elyzol
State
Solid
Elyzol
LogP
-0.262
Elyzol
Dosage Forms
Tablet; Intravenous injection
Elyzol
Indication
Treatment of acute acne rosacea
Elyzol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Elyzol
Absorption
Well absorbed
Elyzol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Elyzol
Patient Information
Elyzol
Organisms Affected
Bacteria and protozoa