Deflamon-Wirkstoff
Brand names,
Deflamon-Wirkstoff
Analogs
Deflamon-Wirkstoff
Brand Names Mixture
Deflamon-Wirkstoff
Chemical_Formula
C6H9N3O3
Deflamon-Wirkstoff
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Deflamon-Wirkstoff
fda sheet
Deflamon-Wirkstoff
msds (material safety sheet)
Deflamon-Wirkstoff
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Deflamon-Wirkstoff
Molecular Weight
171.154 g/mol
Deflamon-Wirkstoff
Melting Point
160 oC
Deflamon-Wirkstoff
H2O Solubility
<0.1g/100mL
Deflamon-Wirkstoff
State
Solid
Deflamon-Wirkstoff
LogP
-0.262
Deflamon-Wirkstoff
Dosage Forms
Tablet; Intravenous injection
Deflamon-Wirkstoff
Indication
Treatment of acute acne rosacea
Deflamon-Wirkstoff
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Deflamon-Wirkstoff
Absorption
Well absorbed
Deflamon-Wirkstoff
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Deflamon-Wirkstoff
Patient Information
Deflamon-Wirkstoff
Organisms Affected
Bacteria and protozoa