Metronidazole in Plastic Container
Brand names,
Metronidazole in Plastic Container
Analogs
Metronidazole in Plastic Container
Brand Names Mixture
Metronidazole in Plastic Container
Chemical_Formula
C6H9N3O3
Metronidazole in Plastic Container
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Metronidazole in Plastic Container
fda sheet
Metronidazole in Plastic Container
msds (material safety sheet)
Metronidazole in Plastic Container
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Metronidazole in Plastic Container
Molecular Weight
171.154 g/mol
Metronidazole in Plastic Container
Melting Point
160 oC
Metronidazole in Plastic Container
H2O Solubility
<0.1g/100mL
Metronidazole in Plastic Container
State
Solid
Metronidazole in Plastic Container
LogP
-0.262
Metronidazole in Plastic Container
Dosage Forms
Tablet; Intravenous injection
Metronidazole in Plastic Container
Indication
Treatment of acute acne rosacea
Metronidazole in Plastic Container
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Metronidazole in Plastic Container
Absorption
Well absorbed
Metronidazole in Plastic Container
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Metronidazole in Plastic Container
Patient Information
Metronidazole in Plastic Container
Organisms Affected
Bacteria and protozoa