Trichazol
Brand names,
Trichazol
Analogs
Trichazol
Brand Names Mixture
Trichazol
Chemical_Formula
C6H9N3O3
Trichazol
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Trichazol
fda sheet
Trichazol
msds (material safety sheet)
Trichazol
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Trichazol
Molecular Weight
171.154 g/mol
Trichazol
Melting Point
160 oC
Trichazol
H2O Solubility
<0.1g/100mL
Trichazol
State
Solid
Trichazol
LogP
-0.262
Trichazol
Dosage Forms
Tablet; Intravenous injection
Trichazol
Indication
Treatment of acute acne rosacea
Trichazol
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Trichazol
Absorption
Well absorbed
Trichazol
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Trichazol
Patient Information
Trichazol
Organisms Affected
Bacteria and protozoa