Flegyl
Brand names,
Flegyl
Analogs
Flegyl
Brand Names Mixture
Flegyl
Chemical_Formula
C6H9N3O3
Flegyl
RX_link
http://www.rxlist.com/cgi/generic2/metron.htm
Flegyl
fda sheet
Flegyl
msds (material safety sheet)
Flegyl
Synthesis Reference
Jacob et al., U.S. Pat. 2,944,061 (1960)
Flegyl
Molecular Weight
171.154 g/mol
Flegyl
Melting Point
160 oC
Flegyl
H2O Solubility
<0.1g/100mL
Flegyl
State
Solid
Flegyl
LogP
-0.262
Flegyl
Dosage Forms
Tablet; Intravenous injection
Flegyl
Indication
Treatment of acute acne rosacea
Flegyl
Pharmacology
Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn's disease, antibiotic-associated diarrhea, and rosacea.
Flegyl
Absorption
Well absorbed
Flegyl
side effects and Toxicity
Convulsive seizures and peripheral neuropathy, the latter characterized mainly by numbness or paresthesia of an extremity, LD50=500 mg/kg/day (orally in rat)
Flegyl
Patient Information
Flegyl
Organisms Affected
Bacteria and protozoa