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Genphen Brand names, Genphen Analogs

Genphen Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Genphen Chemical_Formula


Genphen RX_link

Genphen fda sheet

Genphen FDA

Genphen msds (material safety sheet)

Genphen Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Genphen Molecular Weight

284.42 g/mol

Genphen Melting Point


Genphen H2O Solubility

Freely soluble

Genphen State


Genphen LogP


Genphen Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Genphen Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Genphen Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Genphen Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Genphen side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Genphen Patient Information

Genphen Organisms Affected

Humans and other mammals