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Fellozine Brand names, Fellozine Analogs

Fellozine Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Fellozine Chemical_Formula


Fellozine RX_link


Fellozine fda sheet

Fellozine FDA

Fellozine msds (material safety sheet)

Fellozine Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Fellozine Molecular Weight

284.42 g/mol

Fellozine Melting Point


Fellozine H2O Solubility

Freely soluble

Fellozine State


Fellozine LogP


Fellozine Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Fellozine Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Fellozine Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Fellozine Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Fellozine side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Fellozine Patient Information

Fellozine Organisms Affected

Humans and other mammals