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Fargan Brand names, Fargan Analogs

Fargan Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Fargan Chemical_Formula


Fargan RX_link


Fargan fda sheet

Fargan FDA

Fargan msds (material safety sheet)

Fargan Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Fargan Molecular Weight

284.42 g/mol

Fargan Melting Point


Fargan H2O Solubility

Freely soluble

Fargan State


Fargan LogP


Fargan Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Fargan Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Fargan Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Fargan Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Fargan side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Fargan Patient Information

Fargan Organisms Affected

Humans and other mammals