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Phargan Brand names, Phargan Analogs

Phargan Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Phargan Chemical_Formula


Phargan RX_link

Phargan fda sheet

Phargan FDA

Phargan msds (material safety sheet)

Phargan Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Phargan Molecular Weight

284.42 g/mol

Phargan Melting Point


Phargan H2O Solubility

Freely soluble

Phargan State


Phargan LogP


Phargan Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Phargan Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Phargan Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Phargan Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Phargan side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Phargan Patient Information

Phargan Organisms Affected

Humans and other mammals