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Phensedyl Brand names, Phensedyl Analogs

Phensedyl Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Phensedyl Chemical_Formula


Phensedyl RX_link

Phensedyl fda sheet

Phensedyl FDA

Phensedyl msds (material safety sheet)

Phensedyl Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Phensedyl Molecular Weight

284.42 g/mol

Phensedyl Melting Point


Phensedyl H2O Solubility

Freely soluble

Phensedyl State


Phensedyl LogP


Phensedyl Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Phensedyl Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Phensedyl Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Phensedyl Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Phensedyl side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Phensedyl Patient Information

Phensedyl Organisms Affected

Humans and other mammals