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Phencen Brand names, Phencen Analogs

Phencen Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Phencen Chemical_Formula


Phencen RX_link

Phencen fda sheet

Phencen FDA

Phencen msds (material safety sheet)

Phencen Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Phencen Molecular Weight

284.42 g/mol

Phencen Melting Point


Phencen H2O Solubility

Freely soluble

Phencen State


Phencen LogP


Phencen Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Phencen Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Phencen Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Phencen Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Phencen side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Phencen Patient Information

Phencen Organisms Affected

Humans and other mammals