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Dimapp Brand names, Dimapp Analogs

Dimapp Brand Names Mixture

  • Phenergan VC Expectorant Syrup (Phenylephrine hydrochloride + Potassium guaiacol sulphonate + Promethazine hydrochloride)

Dimapp Chemical_Formula


Dimapp RX_link


Dimapp fda sheet

Dimapp FDA

Dimapp msds (material safety sheet)

Dimapp Synthesis Reference

Charpentier, U.S. Pat. 2,503,451 (1950)

Dimapp Molecular Weight

284.42 g/mol

Dimapp Melting Point


Dimapp H2O Solubility

Freely soluble

Dimapp State


Dimapp LogP


Dimapp Dosage Forms

Tablet; Suppository; Opthalmic drops; Syrup

Dimapp Indication

For the treatment of allergic disorders, itching, nausea and vomiting.

Dimapp Pharmacology

Promethazine, a phenothiazine, is an H1-antagonist with anticholinergic, sedative, and antiemetic effects and some local anesthetic properties. Promethazine is used as an antiemetic or to prevent motion sickness.

Dimapp Absorption

On average, 88% of a promethazine dose is absorbed after oral administration; however, the absolute bioavailability is only 25% because of first-pass clearance.

Dimapp side effects and Toxicity

Symptoms of overdose include mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). LD50=55mg/kg (I.V. in mice)

Dimapp Patient Information

Dimapp Organisms Affected

Humans and other mammals